Methicillin-Resistant Staphylococcus Aureus | Antibiotics & Antimicrobial Resistance 2020

Meticillin‐resistant staph aureus (MRSA) continues to cause a serious threat to human health. In animals, MRSA has become established as a veterinary infectious agent in pets and horses; in eutherian mammal, it presents a priority for public health as a reservoir that may infect humans and as a supply of transferrable resistance genes.


Genetic analyses have discovered that the medicine of MRSA is completely different in numerous animal hosts. whereas human hospital‐associated MRSA lineages area unit most typically concerned in pet infection and carriage, horse‐specific MRSA most frequently represent ‘traditional’ equine S. aureus lineages. A recent development within the medicine of animal MRSA is that the emergence of pig‐adapted strains, like CC398 and CC9, that seem to possess arisen severally within the pig population.

Recent insight into the order structure and also the evolution of S. aureus has helped to clarify key aspects of those 3 distinct medical specialty eventualities. This nonsystematic literature review summarizes the structure and variations of the S. aureus order and offers an outline of this distribution of MRSA lineages in varied animal species. It additionally discusses gift data concerning the emergence and evolution of MRSA in animals, adaptation to completely different host species and response to selective pressure from animal‐specific environments.


An improved understanding of the biology and selective pressure that underpin the accommodative behaviour of S. aureus is also employed in the long run to predict new developments in cocci diseases and to research novel management ways needed at a time of skyrocketing resistance to antimicrobial agents.

Contact: Erika Madison
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